We work together with other researchers, NIH-funded cohorts, and local community partners on projects that aim to provide a better understanding of adverse maternal exposures in early pregnancy and their long-term effects on child health.
The Infant Development and Environment Study is a U.S. multi-center study (CA, WA, MN, NY) designed to examine how everyday chemicals in food, cosmetics, and household products may affect children’s health and development.
We are studying the role of placental biomarkers in the association of prenatal phthalates and infant genital and brain-related outcomes. To do this, we use measures of serum placental-fetal hormones abstracted from the medical record and also placental tissue samples collected from a subset of pregnancies at the TIDES UCSF site.
Joint publication: PMID: 26200238
Conditions Affecting Neurocognitive Development and Learning in Early Childhood is a longitudinal cohort study that studies factors during pregnancy that impact the baby’s development in their first three years of life.
With biospecimens from a pilot sample (N=50), we measure associations of prenatal phthalate exposures with circulating placental and maternal biomarkers, and infant cognition at one and three years of age.
Joint publication: PMID: 33928202
Understanding Pregnancy Signals and Infant Development is a birth cohort study to learn about how the ways in which a mother’s daily environment and changing emotions may affect her baby’s development.
To evaluate the hypothesis that placental hCG mediates the association between prenatal phthalates and anogenital distance, we are measuring urinary phthalates and placental hormones in maternal circulation.
We work closely with the University of Pittsburgh Medical Center’s Magee Womens Hospital and the Magee Obstetric Maternal & Infant Database and Biobank that collects obstetric biological samples.
We are measuring urinary phthalate levels and placental biomarkers in serum and in placental tissue to evaluate hypotheses on exposures in the context of the 2020-2021 COVID-19 pandemic. These include food environment changes that affected phthalate levels, structural and individual level racial discrimination, and SARS-CoV-2 exposure.
Additionally, we currently use MOMI Biobank samples to teach a course entitled, “The Application of Molecular Biomarkers in Epidemiology”.
5132 Public Health
130 Desoto Street
Pittsburgh, PA 15261
adibij [@] pitt.edu